Typical trifoliata ranges widely from southeastern states to the Great Lakes region, but it is rare to absent in more extensive lowlands of the lower Ohio and lower Mississippi Valley, and in much of the central Appalachians (K). It is patchily distributed, perhaps reflecting association with areas that have a long history of brushy openings in the woodland. Although usually found on rocky calcareous sites, it can also occur on deeper soils, where its running roots and low palatability may allow it to resist local disturbance from browsing. Ptelea and Zanthoxylum are hosts for the Giant Swallowtail butterfly, which also is a pest of citrus further south.